Relationship between intracranial pressure and neurocognitive function among older adults after radical resection of rectal cancer

Table 2 Statistical analysis of Mini-Mental State Examination score and confusion assessment method score of two groups

	Timepoints/ANOVA factors	Group A1	Group A2	F value	P value
CAM	1 day before surgery	10.98 ± 1.00	11.08 ± 0.99	0.272	0.603
	1 day after surgery	14.93 ± 0.81	12.37 ± 1.64	88.2	< 0.001
	4 days after surgery	16.62 ± 1.78	14.62 ± 1.38	41.736	< 0.001
	7 days after surgery	12.93 ± 0.92	12.76 ± 0.61	1.239	0.268
	Time effect			213.73a	0.012a
	Group effect			66.18a	0.031a
	Interaction effect			21.41a	0.022a
MMSE	1 day before surgery	29.29 ± 0.51	29.37 ± 0.60	0.493	0.484
	1 day after surgery	23.79 ± 1.32	27.97 ± 1.26	268.665	< 0.001
	4 days after surgery	24.64 ± 1.10	28.08 ± 0.79	347.358	< 0.001
	7 days after surgery	28.74 ± 1.06	28.89 ± 0.88	0.626	0.431
	Time effect			261.59	0.003
	Group effect			312.85	0.025
	Interaction effect			113.94	0.025

^aP value of Mauchly’s spherical test is less than 0.05, and the F value or P value has been corrected by Greenhouse-Geisser. The P value of the group effect of the above indicators is less than 0.05, indicating that the group A1 and A2 have statistically significant differences in the effects of confusion assessment method and Mini-Mental State Examination. In addition, the P value of the interaction effect of confusion assessment method and Mini-Mental State Examination is less than 0.05, and the individual effect is reflected in the statistical difference at t2 and t3.

CAM: Confusion assessment method; MMSE: Mini-Mental State Examination.