Risk factors and survival prediction model establishment for prognosis in patients with radical resection of gallbladder cancer

Table 3 Univariate analysis of prognostic factors in patients undergoing radical surgery for gallbladder cancer, n (%)

Factor	Frequency/percentage	HR (95%CI)	P value
Sex
Male	38 (40.9)	-
Female	55 (59.1)	0.75 (0.45-1.23)	P = 0.248
Age
< 57	25 (26.9)	-
≥ 57	68 (73.1)	1.51 (0.84-2.70)	P = 0.165
CA19-9
Negative	52 (55.9)	-
Positive	41 (44.1)	5.05 (2.97-8.60)	P < 0.001
T stage
T1-T2	29 (31.2)	-
T3-T4	64 (68.8)	7.62 (3.44-16.87)	P < 0.001
Lymph node metastasis
N0	54 (58.1)	-
N1	34 (36.6)	4.18 (2.44-7.15)	P < 0.001
N2	5 (5.4)	4.69 (1.79-12.26)	P = 0.002
Differentiation degree
Well-differentiated	25 (26.9)	-
Moderately differentiated	23 (24.7)	10.28 (3.50-30.21)	P < 0.001
Poorly differentiated	45 (48.4)	11.38 (4.03-32.11)	P < 0.001
Surgical margin
Negative	83 (89.2)	-
Positive	10 (10.8)	3.10 (1.54-6.22)	P = 0.002
Liver invasion
Absent	50 (53.8)	-
Present	43 (46.2)	6.91 (3.99-11.97)	P < 0.001

HR: Hazard ratio; CA19-9: Carbohydrate antigen 19-9.