Local excision of early rectal cancer: A multi-centre experience of transanal endoscopic microsurgery from the United Kingdom

doi:10.4240/wjgs.v16.i10.3114

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Oct 27, 2024 (publication date) through Sep 27, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. Oct 27, 2024; 16(10): 3114-3122
Published online Oct 27, 2024. doi: 10.4240/wjgs.v16.i10.3114

Table 4 Factors affecting disease-free survival and overall survival

Factors affecting survival	DFS		OS
Factors affecting survival	95%CI	P value	95%CI	P value
Age		P = 0.35 (NS)		P = 0.022
Gender		P = 0.83 (NS)		P = 0.174 (NS)
Male	120 (111-129.5)		96.6 (86.6-106.7)
Female	123.6 (110.9-136.3)		107.7 (93.6-120.7)
Distance from AV		P = 0.953 (NS)		P = 0.0001
Tumour size		P = 0.17 (NS)		P = 0.0001
pT	pT0: 111.3 (93-129.4); pT1: 123.8 (111.3-134.3); pT2: 118 (105.4-131.9); pT3: 94 (72.9-116)	P = 0.45 (NS)	pT0: 102 (79.5-125.7); pT1: 115 (104-126); pT2: 86 (75-97.3); pT3: 54.3 (42.5-66)	P = 0.000039
pN0	93.6 (76.5-110.7)		77.6 (58.7-96.5)
pN1	101.7 (81.4-121.9)	P = 0.82 (NS)	101.7 (86.9-116.5)	P = 0.57 (NS)
R0	123.2 (114.7-131.6)		105.7 (96.5-114.9)
R1	92 (72-112)	P = 0.047	74.7 (61.2-88.2)	P = 0.045
Salvage TME	92.5 (74-111.2)		111 (96.6-125.2)
No Salvage TME	110.3 (98-123)	P = 0.121 (NS)	101.4 (88.7-114.2)	P = 0.21 (NS)

OS: Overall survival; DFS: Disease-free survival; NS: Not statistically significant; AV: Anal verge; CI: Confidence interval; TME: Total mesorectal excision.

Citation: Farid A, Tutton M, Thambi P, Gill T, Khan J. Local excision of early rectal cancer: A multi-centre experience of transanal endoscopic microsurgery from the United Kingdom. World J Gastrointest Surg 2024; 16(10): 3114-3122
URL: https://www.wjgnet.com/1948-9366/full/v16/i10/3114.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i10.3114