Editorial
Copyright ©The Author(s) 2024.
World J Gastrointest Surg. Oct 27, 2024; 16(10): 3094-3103
Published online Oct 27, 2024. doi: 10.4240/wjgs.v16.i10.3094
Table 2 Minimally invasive vs open pancreaticoduodenectomy published randomized clinical trials
Palanivelu 2017 (PLOT), Lps vs Open[50]Poves 2018 (PADULAP), Lps vs Open[51]Van Hilst 2019 (LEOPARD 2), Lps vs Open[52]Wang 2021, Lps vs Open[53]Klotz 2024 (EUROPA), Robotic vs Open[62]Liu 2024, Robotic vs Open[63]
Enrollment period2013-20152013-20172016-20172018-20192020-20222022
MIOpMIOpMIOpMIOpMIOpMIOp
n32323432505929729729338180
OT (minute)3593200.0414863650.0014102740.0013253000.0014313670.0212452980.001
EBL (mL)2504010.001300450NS2003000.001742814NS751500.001
CR-POPF (%)612NS1328NS2824NS1011NS3821NS1413NS
Bile leakage (%)96NS310NS1210NS1314NS179NS1623NS
Gastro/duodenojejunal fistula (%)00NS40NS
Chyle leak (%)4140.0973NS
DGE (%)1622NS924NS3420NS3032NS3460.0052533NS
PPH (%)912NS921NS1014NS1311NS143NS1419NS
SSI (%)12250.0154140.091010NS1011NS
Reintervention (%)33NS3170.06126NS34NS1415NS34NS
Severe morbidity (Clavien-Dindo ≥ 3) (%)912NS16380.0485039NS2923NS2224NS
LOS, days7130.00113.5170.0241110NS15160.021713NS1113.50.029
Readmission (%)69NS2214NS1620NS32NS1716NS76NS
90-day mortality (%)33NS02NS102NS22NS0911NS
R0 (%)9794NS6052NS8276NS9897NS80100NS9696NS
N harvested Lymph nodes (n)1817NS1521NS1111NS1213NS2926NS1313NS