Quantitative evaluation of colorectal tumour vasculature using contrast-enhanced ultrasound: Correlation with angiogenesis and prognostic significance

Table 3 Associations between contrast-enhanced ultrasound parameters, angiogenesis markers, and clinicopathological characteristics

	Tumour stage	Lymph node metastasis	Distant metastasis	Age (yr)	Sex
PI	P < 0.001	P < 0.001	P < 0.001	NS	NS
TTP	P < 0.001	P < 0.001	P < 0.001	NS	NS
AUC	P < 0.001	P < 0.001	P < 0.001	NS	NS
VEGF expression	P < 0.001	P < 0.001	P < 0.001	NS	NS
MVD	P < 0.001	P < 0.001	P < 0.001	NS	NS

NS: No significant; PI: Peak intensity; TTP: Time to peak; AUC: Area under the curve; VEGF: Vascular endothelial growth factor; MVD: Microvessel density.