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©The Author(s) 2023.
World J Gastrointest Surg. Sep 27, 2023; 15(9): 2032-2041
Published online Sep 27, 2023. doi: 10.4240/wjgs.v15.i9.2032
Published online Sep 27, 2023. doi: 10.4240/wjgs.v15.i9.2032
Table 2 Demographic analysis of patients according to preoperative and postoperative syndecan-2 methylation test
Characteristics | Preoperative (n = 123) | Postoperative (n = 122) | ||||
Negative, n = 14 (%) | Positive, n = 109 (%) | P value | Negative, n = 98 (%) | Positive, n = 24 (%) | P value | |
Sex | 0.375 | 0.030 | ||||
Male | 11 (78.6) | 69 (63.3) | 68 (69.4) | 11 (45.8) | ||
Female | 3 (21.4) | 40 (36.7) | 30 (30.6) | 13 (54.2) | ||
Age, yr | 0.512 | 0.845 | ||||
< 65 | 9 (64.3) | 60 (55.0) | 55 (56.1) | 14 (58.3) | ||
≥ 65 | 5 (35.7) | 49 (45.0) | 43 (43.9) | 10 (41.7) | ||
Location | 0.664 | 0.079 | ||||
Right colon | 5 (35.7) | 30 (27.5) | 34 (34.7) | 3 (12.5) | ||
Left colon | 7 (50.0) | 51 (46.8) | 42 (42.9) | 12 (50.0) | ||
Rectum | 2 (14.3) | 28 (25.7) | 22 (22.4) | 9 (37.5) | ||
Histology | 0.226 | 1.000 | ||||
WD/MD | 12 (85.7) | 103 (94.5) | 92 (93.9) | 23 (95.8) | ||
PD/Mucinous | 2 (14.3) | 6 (5.5) | 6 (6.1) | 1 (4.2) | ||
Tumor size, cm | 0.019 | 0.145 | ||||
< 3 | 10 (71.4) | 42 (38.5) | 41 (41.8) | 14 (58.3) | ||
≥ 3 | 4 (28.6) | 67 (61.5) | 57 (58.2) | 10 (41.7) | ||
T stage | 0.033 | 0.137 | ||||
Tis-T2 | 9 (64.3) | 34 (31.2) | 33 (33.7) | 12 (50.0) | ||
T3-T4 | 5 (35.7) | 75 (68.8) | 65 (66.3) | 12 (50.0) | ||
N stage | 0.769 | 0.152 | ||||
N0 | 10 (71.4) | 70 (64.2) | 58 (59.2) | 18 (75.0) | ||
N+ | 4 (28.6) | 39 (35.8) | 40 (40.8) | 6 (25.0) | ||
TNM stage | 0.769 | 0.152 | ||||
0-II | 10 (71.4) | 70 (64.2) | 58 (59.2) | 18 (75.0) | ||
III-IV | 4 (28.6) | 39 (35.8) | 40 (40.8) | 6 (25.0) | ||
TCF before surgery | 0.627 | 0.685 | ||||
Not done | 2 (14.3) | 10 (9.2) | 9 (9.2) | 1 (4.2) | ||
Done | 12 (85.7) | 99 (90.8) | 89 (90.8) | 23 (95.8) | ||
RAA | 0.692 | 0.172 | ||||
Not present | 13 (92.9) | 94 (86.2) | 88 (89.8) | 19 (79.2) | ||
Present | 1 (7.1) | 15 (13.8) | 10 (10.2) | 5 (20.8) |
- Citation: Song JH, Oh TJ, An S, Lee KH, Kim JY, Kim JS. Comparative detection of syndecan-2 methylation in preoperative and postoperative stool DNA in patients with colorectal cancer. World J Gastrointest Surg 2023; 15(9): 2032-2041
- URL: https://www.wjgnet.com/1948-9366/full/v15/i9/2032.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v15.i9.2032