Regional differences in islet amyloid deposition in the residual pancreas with new-onset diabetes secondary to pancreatic ductal adenocarcinoma

Figure 2 Islet immunohistochemical and immunofluorescent analysis of the proximal/distal pancreas of pancreatic ductal adenocarcinoma patients with new-onset diabetes. A and B: Representative images of immunohistochemical staining for insulin from the proximal (A) or distal (B) pancreas; C and D: Representative quadruple insulin (red), glucagon (green), thioflavin T (white) and DAPI (blue) staining from the proximal (C) or distal (D) pancreas for the determination of β-cell area, α-cell area and amyloid deposits.