Prognosis after splenectomy plus pericardial devascularization vs transjugular intrahepatic portosystemic shunt for esophagogastric variceal bleeding

Table 4 Multivariate Cox regression analysis of factors associated with variceal rebleeding, abnormal liver function, and hepatocellular carcinoma

Outcome/Variable	HR (95%CI)	P value
Variceal rebleeding
Treatment strategy (SPD vs TIPS)	0.58 (0.37-0.89)	0.01
GGT, per 1 IU/L increase	1.005 (1.001-1.008)	0.01
HGB, per 1 g/L increase	0.99 (0.98-1.00)	0.01
Abnormal liver function
Treatment Strategy (SPD vs TIPS)	0.26 (0.17-0.39)	< 0.001
TB, per 1 μmol/L increase	1.03 (1.02-1.05)	< 0.001
ALP, per 1 IU/L increase	1.004 (1.000-1.007)	0.03
PT, per 1 s increase	1.06 (1.00-1.13)	0.045
Hepatocellular carcinoma
Treatment Strategy (SPD vs TIPS)	0.43 (0.20-0.93)	0.03
TB, per 1 μmol/L increase	1.03 (1.00-1.07)	0.045
ALP, per 1 IU/L increase	1.006 (1.000-1.012)	0.043

SPD: Splenectomy plus pericardial devascularization; TIPS: Transjugular intrahepatic portosystemic shunt; TB: Total bilirubin; ALB: albumin; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; PT: Prothrombin time; HGB: Hemoglobin.