Prognosis after splenectomy plus pericardial devascularization vs transjugular intrahepatic portosystemic shunt for esophagogastric variceal bleeding

Table 2 Univariate and multivariate Cox regression analyses of factors associated with death

Variable	Univariable analysis		Multivariable analysis
	HR (95%CI)	P value1	HR (95%CI)	P value
Treatment strategy (SPD vs TIPS)	0.43 (0.24-0.78)	0.005	0.47 (0.25-0.90)	0.02
Age, per 1-year increase	1.04 (1.02-1.07)	0.001	1.03 (1.01-1.06)	0.02
TB, per 1 μmol/L increase	1.03 (1.01-1.06)	0.01
ALB, per 1 g/L increase	0.94 (0.91-0.98)	0.004
A/G, per 1 increase	0.06 (0.02-0.18)	< 0.001	0.11 (0.03-0.48)	0.003
ALP, per 1 IU/L increase	1.01 (1.00-1.01)	< 0.001
GGT, per 1 IU/L increase	1.003 (1.00-1.01)	0.03
PT, per 1 s increase	1.07 (1.02-1.12)	0.004	1.09 (1.02-1.16)	0.01
INR, per 1 increase	6.38 (1.68-24.24)	0.006
HBV-DNA (Positive vs negative)	1.78 (1.00-3.15)	0.05
Child-Pugh classification (B vs A)	1.83 (1.07-3.15)	0.03

¹Variables that were found significant at P < 0.1 in the univariable analyses were entered into the multivariable analyses. SPD: Splenectomy plus pericardial devascularization; TIPS: Transjugular intrahepatic portosystemic shunt; TB: Total bilirubin; ALB: Albumin; A/G: Albumin/globulin; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; PT: Prothrombin time; INR: International normalized ratio; HBV: Hepatitis B virus.