Resection of isolated liver oligometastatic disease in pancreatic ductal adenocarcinoma: Is there a survival benefit? A systematic review

Table 1 Characteristics of included studies

Ref.	Country and Units	Single or multicentre	Metastasectomy timing	Control group?	Total patients included	Total no controls	Gender (% male)	Pancreas resection types included
Dünschede et al[23], 2010	Germany	Single	Metachronous and synchronous	Yes	13	10	54	PD, DP, TP
Hackert et al[31], 2017	Germany	Single	Metachronous and synchronous	No	85	-	55	PD, DP, TP
Hamad et al[24], 2022	United States	Single	Synchronous only	Yes	137	-	-	PD only
Klein et al[25], 2012	Germany	Single	Synchronous only	Yes	22	22	64	PD, DP, TP
Shi et al[32], 2016	China	Single	Synchronous only	Yes	30	39	67	PD, DP, TP
Schwarz et al[26], 2020	Germany, Austria and United States	Multicentre	Metachronous only	Yes	25	8	42	NR
Tachezy et al[27], 2016	Greece, France, Italy and Germany	Multicentre	Synchronous only	Yes	69	69	63	PD, DP, TP
Takeda et al[28], 2023	Japan	Single	Synchronous only	Yes	5	-	80	NR
Yang et al[29], 2020	China	Single	Synchronous only	Yes	48	10	58	PD, DP
Zanini et al[30], 2015	Italy	Single	Metachronous and synchronous	No	15	-	53	PD, DP, TP

PDAC: Pancreatic ductal adenocarcinoma; PD: Pancreatoduodenectomy; DP: Distal pancreatectomy; TP: Total pancreatectomy; NR: Not reported.