Nutritional status efficacy of early nutritional support in gastrointestinal care: A systematic review and meta-analysis

Table 1 Basic characteristics, patient characteristics, and outcome indicators of the included literatures

Ref.	Year	Design	Intention-to-treat total	Sample (E/D)	Surgery type	Age (yr)	Nutrition support mode	Outcomes
Sun et al[11]	2017	A prospective, randomized, single-blinded, controlled study	107	53/54	Major abdominal surgery	56 ± 10	Oral feeding	e, f
Pragatheeswarane et al[12]	2014	A randomized controlled study	120	60/60	Elective open bowel surgeries	46.5 ± 17.2	Oral feeding	d, e, f
Dag et al[13]	2011	A randomized controlled study	199	99/100	Elective open colorectal cancer surgery	62 (35-85)	Oral feeding	d, e, f
Fujii et al[14]	2014	A controlled study	120	62/58	Elective colorectal resection surgery	67.4 ± 11.7	Oral feeding	a, d, e, f
Liao et al[15]	2020	A randomized controlled study	41	21/20	Esophageal carcinoma surgery	57.2 ± 8.2	Enteral nutrition	d, f
Mi et al[16]	2012	A randomized controlled study	60	30/30	Gastrectomy	57.2 ± 9.5	Oral feeding	a, b, d, f
Mahmoodzadeh et al[17]	2015	A randomized controlled study	109	54/55	Gastrointestinal surgeries	64.2 ± 8.2	Oral feeding	d, f
Wang et al[18]	2005	A retrospective comparative study	454	227/227	Colorectal cancer resection surgery	63.5 ± 11.3	Enteral nutrition	d, e, f
Qiu et al[19]	2020	A retrospective comparative study	26	13/13	Severe acute pancreatitis treatment	33.4 ± 5.7	Enteral nutrition	a, c, d
Wang et al[20]	2015	A randomized controlled study	188	101/87	Esophagectomy	59.5 ± 8.4	Enteral nutrition	a, c, d, e, f
Klappenbach et al[21]	2013	A randomized controlled study	295	148/147	Abdominal elective surgery	37.3 ± 18.1	Oral feeding	d, e, f
Li et al[22]	2015	A randomized controlled study	300	150/150	Gastric cancer surgery	59.2 ± 9.7	Enteral nutrition	a, b, d, f
Zou et al[23]	2014	A retrospective comparative study	93	46/47	Severe acute pancreatitis treatment	46.5 (34.6-59.3)	Enteral nutrition	a, d, f
Barlow et al[24]	2011	A randomized controlled study	121	64/57	Upper gastrointestinal cancer surgery	64.0 ± 15.0	Eternal feeding	f

a: Albumin (g/L); b: Prealbumin (g/L); c: Total serum protein (g/L); d: Length of stay (d); e: Time to first defecation (h); f: Complications rate; E/D: Early/delayed.