Retrospective efficacy analysis of olaparib combined with bevacizumab in the treatment of advanced colorectal cancer

doi:10.4240/wjgs.v15.i5.906

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May 27, 2023 (publication date) through Dec 18, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Surg. May 27, 2023; 15(5): 906-916
Published online May 27, 2023. doi: 10.4240/wjgs.v15.i5.906

Table 4 Comparison of tumor marker levels between the two groups

Group	HE4 (pmol/L)		CA125 (ng/mL)		CA199 (U/mL)
Group	Before treatment	After treatment	Before treatment	After treatment	Before treatment	After treatment
Control group (n = 43), mean ± SD	343.75 ± 51.26	184.65 ± 22.34^a	82.43 ± 11.27	58.56 ± 6.08^a	119.60 ± 15.62	82.84 ± 9.28^a
Observation group (n = 39), mean ± SD	349.81 ± 45.79	121.36 ± 19.48^a	83.26 ± 10.33	35.61 ± 4.25^a	121.03 ± 19.85	56.37 ± 7.41^a
t	0.562	13.610	0.346	19.618	0.364	14.177
P value	0.576	< 0.001	0.730	< 0.001	0.717	< 0.001

^aP < 0.05 vs before treatment in the same group. HE4: Human epididymis protein 4; CA125: Carbohydrate antigen 125; CA199: Carbohydrate antigen 199.

Citation: Jiang YL, Fu XY, Yin ZH. Retrospective efficacy analysis of olaparib combined with bevacizumab in the treatment of advanced colorectal cancer. World J Gastrointest Surg 2023; 15(5): 906-916
URL: https://www.wjgnet.com/1948-9366/full/v15/i5/906.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i5.906