Elderly patients over 80 years undergoing colorectal cancer resection: Development and validation of a predictive nomogram for survival

Table 2 Univariate and multivariate Cox regression on predictors for the overall survival of elderly colorectal cancer patients undergoing surgery

	Univariate		Multivariate
	HR (95%CI)	P value	HR (95%CI)	P value
Age1	1.08 (1.02-1.14)	0.005	1.10 (1.04-1.17)	< 0.001
Age
80-89	Reference
90-99	1.31 (0.63-2.73)	0.470	-	-
BMI (kg/m2)
≥ 18.5	Reference		Reference
< 18.5	1.93 (1.12-3.33)	0.018	1.93 (1.05-3.53)	0.034
Serum albumin (g/dL)
≥ 3.0	Reference		Reference
2.5-3.0	1.75 (0.90-3.44)	0.101	1.18 (0.55-2.54)	0.672
< 2.5	7.15 (2.82-18.2)	< 0.001	5.04 (1.82-13.9)	0.002
TNM staging
I, II, and III	Reference		Reference
IV	3.95 (2.07-7.55)	< 0.001	2.06 (0.95-4.49)	0.068
CCI1	1.34 (1.21-1.48)	< 0.001	1.41 (1.25-1.59)	< 0.001
Priority of operation
Elective	Reference		Reference
Emergency	1.81 (1.13-2.88)	0.013	1.35 (0.78-2.33)	0.278
Postoperative pneumonia
No	Reference		Reference
Yes	3.46 (1.77-6.78)	< 0.001	2.99 (1.43-6.23)	0.004
Postoperative myocardial infarction
No	Reference		Reference
Yes	6.01 (2.17-16.6)	< 0.001	4.09 (1.37-12.2)	0.012

¹Continuous variables. Bold values indicate statistical significance at the P < 0.05 level. HR: Hazard ratio; CI: Confidence interval; BMI: Body mass index; TNM: Tumor-node-metastasis; CCI: Charlson comorbidity index.