Differential expression and significance of 5-hydroxymethylcytosine modification in hepatitis B virus carriers and patients with liver cirrhosis and liver cancer

Figure 1 Principal component analysis after 5-hydroxymethylcytosine sequencing of hepatitis B surface antigen-positive carriers, patients with liver cirrhosis, and patients with liver cancer (40 cases per group). A: Principal component analysis (PCA) plot of all genes in hepatitis B surface antigen (HBsAg)-positive carriers and patients with liver cancer; B: PCA plot of differential genes between HBsAg-positive carriers and patients with liver cancer; C: PCA plot of all genes in patients with liver cirrhosis and those with liver cancer; D: PCA plot of differential genes between patients with liver cirrhosis and those with liver cancer. PCA: Principal component analysis; HBV: Hepatitis B virus.