Differential expression and significance of 5-hydroxymethylcytosine modification in hepatitis B virus carriers and patients with liver cirrhosis and liver cancer

doi:10.4240/wjgs.v15.i3.346

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Mar 27, 2023 (publication date) through Nov 5, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Mar 27, 2023; 15(3): 346-361
Published online Mar 27, 2023. doi: 10.4240/wjgs.v15.i3.346

Table 1 Differential genes between hepatitis B surface antigen-positive carriers and patients with liver cancer after 5-hydroxymethylcytosine sequencing

Symbol	Ensembl	log2FoldChange	padj
SI	ENSG00000090402	0.849003917	0.000172596
FAM83B	ENSG00000168143	0.532487323	0.00425853
PCK1	ENSG00000124253	0.519299173	0.006848676
KCNN2	ENSG00000080709	-0.510730422	0.011078186
FAT1	ENSG00000083857	0.47499449	0.02542581
FGF19	ENSG00000162344	0.428605733	0.036854977
FABP1	ENSG00000163586	0.427372957	0.025268146
SLC10A2	ENSG00000125255	0.417559665	0.005504835
ISX	ENSG00000175329	0.391889896	0.005936182
APOC3	ENSG00000110245	0.374978715	0.017711634
NOVA1	ENSG00000139910	0.367147827	0.006848676
KRT20	ENSG00000171431	0.361001798	0.049694505
DUSP1	ENSG00000120129	0.341097702	0.001523335
RBP2	ENSG00000114113	0.330491105	0.049694505
PCLO	ENSG00000186472	0.307272826	0.000520372
BRINP3	ENSG00000162670	0.297534011	0.001107995
SLC2A2	ENSG00000163581	0.297032232	0.006630228
AKR1B10	ENSG00000198074	0.296134756	0.012660193
SEMA3A	ENSG00000075213	0.295498456	7.92E-05
SLC5A1	ENSG00000100170	0.295343232	0.027331533
ROBO1	ENSG00000169855	0.294408057	0.026805139
ROPN1B	ENSG00000114547	-0.292505301	0.002291301
PRR16	ENSG00000184838	0.291799543	0.049694505
TNFSF15	ENSG00000181634	0.286998557	0.01533013
CDH17	ENSG00000079112	0.284940571	0.001204498
MUC17	ENSG00000169876	0.284637524	0.022168549
PCDH7	ENSG00000169851	0.284173648	0.00131498
FOS	ENSG00000170345	0.28075648	0.008754834
GABRA2	ENSG00000151834	0.27973066	0.049694505
NRCAM	ENSG00000091129	0.270536808	0.047702973
DPP10	ENSG00000175497	0.268657512	0.005504835

Citation: Li YC, Hu WY, Li CH, Zhang LL, Xu XW, Li J, Luo HX. Differential expression and significance of 5-hydroxymethylcytosine modification in hepatitis B virus carriers and patients with liver cirrhosis and liver cancer. World J Gastrointest Surg 2023; 15(3): 346-361
URL: https://www.wjgnet.com/1948-9366/full/v15/i3/346.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i3.346