Does size matter for resection of giant versus non-giant hepatocellular carcinoma? A meta-analysis

Table 2 Basic characteristics of included studies, hepatocellular carcinoma ≥ 10 cm

Study	Year	Follow-up, mo	No.	Age, yr	Sex (M/F)	Tumour size, cm	Cirrhosis, n (%)	Child-Pugh class, n (%)
								A	B + C
Allemann et al[15]	2013	25	22	72 (36-88)	NA	13.5 (10-21)	9 (41)	22 (100)	0 (0)
Chang et al[21]	2016	72.5	912	NA	740/162	NA	166 (18)	NA	NA
Choi et al[22]	2009	36	50	50.8 (12.5)	34/16	NA	13 (26)	48 (96)	2 (4)
Fang et al[16]	2019	20	84	NA	76/8	NA	72 (86)	77 (92)	7 (8)
Giuliante et al[23]	2013	NA	37	62.2 (11)	28/9	12 (11-15)	NA	36 (97)	1 (3)
Huang et al[24]	2016	26	127	NA	114/13	NA	90 (71)	NA	NA
Jo et al[25]	2011	30	11	52.4 (8.4)	6/5	14.5 (4.11)	NA	11 (100)	0 (0)
Lee et al[17]	2021	NA	426	55.7 (14.3)	345/81	13.14 (4.95)	NA	NA	NA
Lewis et al[26]	2019	22	16	NA	NA	NA	NA	NA	NA
Liau et al[27]	2005	27	82	62.0 (14.0)	48/34	14.7 (4.1)	8 (10)	73 (89)	5 (6)
Nagano et al[28]	2005	NA	26	56.2 (12.2)	19/7	14.8 (10-30)	5 (19)	22 (85)	NA
Noh et al[14]	2016	26.4	41	55.1 (10.8)	33/8	NA	NA	NA	NA
Poon et al[29]	2002	56	120	50.9 (12.8)	99/21	13.8 (3)	32 (27)	NA	NA
Shah et al[30]	2007	34	24	57.0 (15.0)	NA	13.1 (2.9)	NA	24 (100)	0 (0)
Tanaka et al[31]	2015	39	24	64.5 (54-71)	20/4	13 (11.2-14.1)	7 (29)	20 (83)	1 (4)
Taniai et al[32]	2008	22.5	29	62.0 (9.4)	26/3	13.45 (2.77)	12 (41)	23 (79)	6 (21)
Thng et al[33]	2015	22	23	63 (34-84)	20/3	NA	NA	20 (87)	3 (13)
Wakayama et al[34]	2017	57	54	63.9 (12.7)	43/10	12.4 (3.7)	NA	49 (92)	4 (8)
Yamashita et al[35]	2011	NA	53	60.0 (2.0)	48/5	13.2 (0.4)	NA	38 (72)	15 (28)
Yang et al[37]	2013	NA	258	45.0 (12)	212/46	13.2 (4.1)	171 (66)	217 (84)	41 (16)
Yang et al[36]	2014	NA	304	NA	242/62	NA	NA	250 (83)	16 (5)
Yeh et al[38]	2003	16.4	211	47.8 (13.4)	164/74	13.9 (3.4)	NA	NA	NA
Zhong et al[39]	2017	NA	150	47.3 (10.9)	123/27	12.4 (2.5)	88 (59)	142 (95)	8 (5)
Zhu et al[40]	2015	29.4	244	46.8 (11.3)	209/35	12 (2.3)	67 (27)	210 (86)	34 (14)

HCC: Hepatocellular carcinoma; NA: Not available; M: Male; F: Female.