Minimum platelet count threshold before invasive procedures in cirrhosis: Evolution of the guidelines

Table 3 Threshold of platelet count before trans-arterial chemoembolization: Evolution of the guidelines

Society	Year	Bleeding risk	Platelet count threshold (/μL)	Ref.
National Institute for Health and Care Excellence	2015	Not classified	50000	National Clinical Guideline Centre (UK)[43]
International Coagulation in Liver Disease	2017	Intermediate	“Generally not recommended”	Intagliata et al[30]
American Association for the Study of Liver Diseases	2020	High	“Suggest individualized approaches”	Northup et al[47]
International Society on Thrombosis and Haemostasis	2021	High	Do not correct	Roberts et al[46]
European Association for the Study of the Liver	2022	Low	“Cannot be generally indicated”	European Association for the Study of the Liver[49]