Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22

Figure 6 Interleukin-22BP inhibits the activation of the hepatic signal transducer and activator of transcription 3 pathway after partial hepatectomy. The expression levels of signal transducer and activator of transcription 3 (STAT3), P-STAT3, and CyclinD1 protein in liver tissue of mice in the partial hepatectomy (PHx)-sham group and the PHx-interleukin-22BP group at 6 h after PHx were detected. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. PHx: Partial hepatectomy; Hv: Hepatic vagotomy; STAT3: Signal transducer and activator of transcription 3; IL: Interleukin.