Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22

Figure 2 Hepatic vagotomy reduces interleukin-22 production after partial hepatectomy. A and B: A mouse interleukin (IL)-22 enzyme-linked immunosorbent assay kit was used to quantify the concentration of IL-22 in serum and liver homogenate of mice in each group; C-E: Liver tissues of different groups were obtained at 6 h after partial hepatectomy (PHx), and the expression of IL-22 protein (C and D) and IL-22 mRNA (E) in liver tissues were detected by western blotting and quantitative real-time polymerase chain reaction techniques, respectively (n = 6-10). ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. PHx: Partial hepatectomy; Hv: Hepatic vagotomy; SP: Sham operation.