Impact of hepatectomy and postoperative adjuvant transarterial chemoembolization on serum tumor markers and prognosis in intermediate-stage hepatocellular carcinoma

Table 3 One-way Cox regression analysis

Considerations	Beta value	SE	χ2 value	P value	HR value	95%CI
						Lower limit	Limit
Distinguishing between the sexes	-0.288	0.231	1.556	0.212	0.750	0.477	1.179
Age	0.608	0.243	6.263	0.012a	1.837	1.141	2.958
HBV	0.179	0.288	0.386	0.534	1.196	0.680	2.105
Cirrhosis	0.646	0.232	7.737	0.005b	1.909	1.210	3.009
Child-push grading	0.164	0.257	0.408	0.523	1.178	0.712	1.948
Number of tumours	0.62	0.248	6.261	0.012a	1.859	1.144	3.021
Maximum tumour diameter	0.686	0.234	8.590	0.003b	1.986	1.255	3.143
Degree of tumour differentiation	0.439	0.150	8.557	0.003b	1.551	1.156	2.080
AFP	-1.516	0.329	21.232	< 0.001c	0.220	0.115	0.418
CEA	-0.177	0.242	0.537	0.464	0.838	0.521	1.346
TBIL	0.104	0.231	0.201	0.654	1.109	0.705	1.744
ALT	0.372	0.265	1.969	0.161	1.451	0.863	2.441
AST	-0.321	0.271	1.405	0.236	0.725	0.426	1.234
Treatment programme	0.625	0.232	7.250	0.007b	1.868	1.185	2.945

^aP < 0.05.

^bP < 0.01.

^cP < 0.001.

HR: Hazard ratio; CI: Confidence interval; HBV: Hepatitis B virus; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen; TBIL: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.