Association between the early high level of serum tacrolimus and recurrence of hepatocellular carcinoma in ABO-incompatible liver transplantation

doi:10.4240/wjgs.v15.i12.2727

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Dec 27, 2023 (publication date) through Feb 15, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. Dec 27, 2023; 15(12): 2727-2738
Published online Dec 27, 2023. doi: 10.4240/wjgs.v15.i12.2727

Table 1 Univariate and multivariate Cox-regression analyses of factors associated with graft survival

	Univariate		Multivariate
	HR (95%CI)	P value	HR (95%CI)	P value
Tacrolimus level, post-LT 16 wk	0.82 (0.68-0.99)	0.040		NS
Tacrolimus level, post-LT 24 wk	0.71 (0.52-0.96)	0.029	0.75 (0.56-0.99)	0.048
AMR	6.01 (2.17-16.68)	0.001	5.41 (1.44-20.40)	0.013

HR: Hazard ratio; 95%CI: 95% confidence interval; AMR: Antibody mediated rejection; NS: Not significant.

Citation: Han JW, Choi JY, Jung ES, Kim JH, Cho HS, Yoo JS, Sung PS, Jang JW, Yoon SK, Choi HJ, You YK. Association between the early high level of serum tacrolimus and recurrence of hepatocellular carcinoma in ABO-incompatible liver transplantation. World J Gastrointest Surg 2023; 15(12): 2727-2738
URL: https://www.wjgnet.com/1948-9366/full/v15/i12/2727.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i12.2727