Risk and management of post-operative infectious complications in inflammatory bowel disease: A systematic review

Table 6 Corticosteroids

Ref.	Year	Cohort	Study	Results
Aberra et al[22]	2003	UC and CD; 159 patients	Retrospective 1999-2000	Increased post-operative infection; No increase observed when 6 MCP/AZP were used
Nguyen et al[23]	2014	UC and CD; 15945 patients	Retrospective 2005-2012	Increased post-operative infection
Fumery et al[25] (REMIND group)	2017	CD; 209 patients	Prospective study 2010-2014	Increased overall post-operative complications, intra- and extra-abdominal septic complications
Subramanian et al[24]	2008	UC and CD	Meta-analysis; 7 studies	Increased infectious complications postoperatively and these increase with a dose of > 40 mg/day of corticosteroids
Law et al[14]	2020	UC and CD	Meta-analysis; 35 studies	Increased infectious complications and intra-abdominal infections

CD: Crohn’s disease; UC: Ulcerative colitis; MCP/AZP: Mercaptopurine/azathioprine.