Multi-national observational study to assess quality of life and treatment preferences in patients with Crohn’s perianal fistulas

doi:10.4240/wjgs.v15.i11.2537

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 11

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (1799)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-5) series, Tables (1-5) series.

Item

Count

PDF

WORD

HTML

936

Figures (1-5)

159

Tables (1-5)

142

Sum=1286

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

140

Download

317

Sum=457

Nov 27, 2023 (publication date) through Jul 28, 2024

Times Cited of This Article

Times Cited (2)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Gastrointest Surg. Nov 27, 2023; 15(11): 2537-2552
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2537

Table 2 Baseline demographics and patient characteristics

	Cohort 1	Cohort 2	Cohort 3	Cohorts 2 + 3
	All non-PF CD (n = 620)	CPF no surgery (n = 174)	CPF with surgery (n = 135)	All CPF (n = 309)
Sex, n (%)
Male	360 (58)^a	116 (67)^b	93 (69)^b	209 (68)^c
Age, yr, n (%)¹
21-40	340 (55)^a^,^d^,^e	112 (64)^c	90 (67)^c	202 (65)^c
41-60	208 (34)^b	59 (34)^b	44 (33)^b	103 (33)^b
61-80	72 (12)^a^,^d^,^e	3 (2)^c	1 (1)^c	4 (1)^c
CD flare-up status, n (%)
Recent flare-up	270 (44)^a^,^e	85 (49)^e	87 (64)^c^,^d	172 (56)^c
Comorbidities, n (%)
Asthma	88 (14)^b	27 (16)^b	30 (22)^b	57 (18)^b
Obesity	87 (14)^b	31 (18)^b	22 (16)^b	53 (17)^b
Cardiovascular disease	33 (5)^a^,^e	13 (7)^b	17 (13)^c	30 (10)^c
COPD	17 (3)^e	4 (2)^d	11 (8)^c^,^d	15 (5)^b
Cancer	22 (4)^b	7 (4)^b	7 (5)^b	14 (5)^b
Renal disease	14 (2)^b	6 (3)^b	6 (4)^b	12 (4)^b

^aP < 0.05 vs cohort 2 and 3 combined.

^bNo statistically significant difference versus any other cohort.

^cP < 0.05 vs cohort 1.

^dP < 0.05 vs cohort 2.

^eP < 0.05 vs cohort 3.

¹None of the patients were aged < 21 or > 80 yr.

P values are shown where there is a statistically significant difference between specified cohorts. Bonferroni adjustment was applied when comparing more than 2 groups at P < 0.05. CD: Crohn’s disease; COPD: Chronic obstructive pulmonary disease; CPF: Crohn’s perianal fistulas; PF: Perianal fistulas.

Citation: Karki C, Athavale A, Abilash V, Hantsbarger G, Geransar P, Lee K, Milicevic S, Perovic M, Raven L, Sajak-Szczerba M, Silber A, Yoon A, Tozer P. Multi-national observational study to assess quality of life and treatment preferences in patients with Crohn’s perianal fistulas. World J Gastrointest Surg 2023; 15(11): 2537-2552
URL: https://www.wjgnet.com/1948-9366/full/v15/i11/2537.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i11.2537