Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer

Table 4 Multivariate Cox regression analyses for predicting cause-specific survival in the training cohort

Characteristics	N-stage		PLN		LNR		LODDS
	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
Race	1.066 (1.023-1.111)	0.003	1.080 (1.036-1.126)	< 0.001	1.068 (1.025-1.114)	0.002	1.066 (1.022-1.111)	0.003
Marital status	1.252 (1.178-1.329)	< 0.001	1.240 (1.167-1.317)	< 0.001	1.258 (1.185-1.336)	< 0.001	1.262 (1.189-1.341)	< 0.001
Primary site	0.885 (0.836-0.938)	< 0.001	0.925 (0.873-0.979)	0.008	0.876 (0.826-0.928)	< 0.001	0.858 (0.809-0.909)	< 0.001
Histology	1.155 (1.071-1.245)	< 0.001	1.044 (0.967-1.126)	0.272	1.074 (0.996-1.159)	0.065	1.077 (0.999-1.162)	0.054
Grade	1.270 (1.212-1.331)	< 0.001	1.311 (1.252-1.373)	< 0.001	1.256 (1.200-1.316)	< 0.001	1.244 (1.188-1.303)	< 0.001
T-stage	1.546 (1.471-1.626)	< 0.001	1.609 (1.532-1.690)	< 0.001	1.574 (1.499-1.654)	< 0.001	1.551 (1.477-1.630)	< 0.001
M-stage	5.132 (4.800-5.487)	< 0.001	5.772 (5.399-6.170)	< 0.001	5.017 (4.684-5.373)	< 0.001	4.716 (4.404-5.051)	< 0.001
N-stage	1.783 (1.710-1.860)	< 0.001	/	/	/	/	/	/
PLN	/	/	1.050 (1.046-1.054)	< 0.001	/	/	/	/
LNR	/	/	/	/	5.304 (4.773-5.895)	< 0.001	/	/
LODDS	/	/	/	/	/	/	1.345 (1.321-1.368)	< 0.001

HR: Hazard ratio; CI: Confidence interval; PLN: Positive lymph node; LNR: Lymph node ratio; LODDS: Log odds of positive lymph node.