Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer

doi:10.4240/wjgs.v15.i11.2430

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Nov 27, 2023 (publication date) through Jun 18, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Nov 27, 2023; 15(11): 2430-2444
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2430

Table 3 Multivariate Cox regression analyses for predicting overall survival in the training cohort

Characteristics	N-stage		PLN		LNR		LODDS
Characteristics	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
Gender	1.131 (1.073-1.193)	< 0.001^a	1.103 (1.046-1.164)	< 0.001^a	1.120 (1.062-1.181)	< 0.001^a	1.120 (1.062-1.181)	< 0.001^a
Race	1.046 (1.008-1.086)	0.017^a	1.058 (1.020-1.098)	0.003^a	1.048 (1.010-1.088)	0.013^a	1.045 (1.007-1.085)	0.019^a
Marital status	1.300 (1.233-1.371)	< 0.001^a	1.289 (1.223-1.360)	< 0.001^a	1.307 (1.239-1.378)	< 0.001^a	1.310 (1.243-1.382)	< 0.001^a
Primary site	0.901 (0.856-0.948)	< 0.001^a	0.934 (0.888-0.983)	0.008^a	0.891 (0.847-0.938)	< 0.001^a	0.873 (0.830-0.919)	< 0.001^a
Histology	1.184 (1.108-1.264)	< 0.001^a	1.089 (1.019-1.164)	0.012^a	1.120 (1.048-1.197)	0.001^a	1.125 (1.052-1.202)	0.001^a
Grade	1.256 (1.205-1.309)	< 0.001^a	1.284 (1.232-1.338)	< 0.001^a	1.238 (1.188-1.290)	< 0.001^a	1.230 (1.180-1.281)	< 0.001^a
T-stage	1.433 (1.373-1.495)	< 0.001^a	1.485 (1.425-1.549)	< 0.001^a	1.456 (1.396-1.518)	< 0.001^a	1.439 (1.380-1.501)	< 0.001^a
M-stage	4.645 (4.378-4.928)	< 0.001^a	5.074 (4.783-5.382)	< 0.001^a	4.484 (4.220-4.764)	< 0.001^a	4.254 (4.003-4.519)	< 0.001^a
N-stage	1.636 (1.578-1.697)	< 0.001^a	/	/	/	/	/	/
PLN	/	/	1.048 (1.044-1.052)	< 0.001^a	/	/	/	/
LNR	/	/	/	/	4.736 (4.303-5.213)	< 0.001^a	/	/
LODDS	/	/	/	/	/	/	1.309 (1.288-1.330)	< 0.001^a

^aP < 0.05.

HR: Hazard ratio; CI: Confidence interval; PLN: Positive lymph node; LNR: Lymph node ratio; LODDS: Log odds of positive lymph node.

Citation: Xia HB, Chen C, Jia ZX, Li L, Xu AM. Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer. World J Gastrointest Surg 2023; 15(11): 2430-2444
URL: https://www.wjgnet.com/1948-9366/full/v15/i11/2430.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i11.2430