Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer

doi:10.4240/wjgs.v15.i11.2430

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Nov 27, 2023 (publication date) through Jun 18, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Nov 27, 2023; 15(11): 2430-2444
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2430

Table 2 Univariate Cox regression analyses for predicting overall survival and cause-specific survival in the training cohort

Characteristics	OS		CSS
Characteristics	HR (95%CI)	P value	HR (95%CI)	P value
Age	1.004 (0.999-1.008)	0.090	1.000 (0.995-1.005)	0.896
Gender	1.096 (1.040-1.156)	0.001^a	1.058 (0.996-1.123)	0.067
Race	1.050 (1.013-1.090)	0.009^a	1.073 (1.030-1.118)	0.001^a
Marital status	1.330 (1.262-1.402)	< 0.001^a	1.282 (1.208-1.362)	< 0.001^a
Primary site	0.926 (0.881-0.974)	0.003^a	0.926 (0.875-0.980)	0.007^a
Histology	1.501 (1.409-1.599)	< 0.001^a	1.498 (1.394-1.609)	< 0.001^a
Grade	1.696 (1.631-1.764)	< 0.001^a	1.774 (1.698-1.853)	< 0.001^a
Stage	3.267 (3.149-3.389)	< 0.001^a	4.102 (3.922-4.290)	< 0.001^a
T stage	2.258 (2.169-2.350)	< 0.001^a	2.566 (2.448-2.690)	< 0.001^a
N stage	2.347 (2.271-2.426)	< 0.001^a	2.653 (2.552-2.757)	< 0.001^a
M stage	7.380 (6.988-7.793)	< 0.001^a	8.790 (8.262-9.351)	< 0.001^a
LN examined	0.989 (0.987-0.991)	< 0.001^a	0.988 (0.985-0.991)	< 0.001^a
LN positive	1.085 (1.082-1.087)	< 0.001^a	1.088 (1.085-1.090)	< 0.001^a
LNR	14.557 (13.403-15.811)	< 0.001^a	17.876 (16.324-19.575)	< 0.001^a
LODDS	1.562 (1.541-1.584)	< 0.001^a	1.630 (1.605-1.656)	< 0.001^a
Size	1.006 (0.970-1.043)	0.759	0.999 (0.959-1.040)	0.955

^aP < 0.05.

OS: Overall survival; CSS: Cause-specific survival; HR: Hazard ratio; CI: Confidence interval; LNR: Lymph node ratio; LODDS: Log odds of positive lymph node.

Citation: Xia HB, Chen C, Jia ZX, Li L, Xu AM. Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer. World J Gastrointest Surg 2023; 15(11): 2430-2444
URL: https://www.wjgnet.com/1948-9366/full/v15/i11/2430.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i11.2430