Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer

Table 1 Clinical and pathologic characteristics of patients with early-onset colon cancer in two cohorts

Characteristics	Overall	Training set	Testing set	P value
	n = 26922	n = 18845	n = 8077
Age	44.00 (39.00, 47.00)	44.00 (39.00, 47.00)	44.00 (39.00, 47.00)	0.730
LN examined	19.00 (14.00, 27.00)	19.00 (14.00, 27.00)	19.00 (14.00, 27.00)	0.959
LN positive	1.00 (0.00, 4.00)	1.00 (0.00, 4.00)	1.00 (0.00, 4.00)	0.800
LNR	0.03 (0.00, 0.19)	0.03 (0.00, 0.19)	0.03 (0.00, 0.20)	0.851
LODDS	-2.66 (-3.66, -1.29)	-2.66 (-3.61, -1.30)	-2.71 (-3.66, -1.24)	0.881
Survival months	51.00 (21.00, 105.00)	51.00 (21.00, 106.00)	50.00 (21.00, 103.00)	0.169
Gender (%)				0.856
Female	13367 (49.7)	9364 (49.7)	4003 (49.6)
Male	13555 (50.3)	9481 (50.3)	4074 (50.4)
Race (%)				0.898
White	19659 (73.0)	13783 (73.1)	5876 (72.7)
Blake	4050 (15.0)	2829 (15.0)	1221 (15.1)
Others	2985 (11.1)	2073 (11.0)	912 (11.3)
Unknown	228 (0.8)	160 (0.8)	68 (0.8)
Marital status (%)				0.383
Married	15296 (56.8)	10674 (56.6)	4622 (57.2)
Others/unknown	11626 (43.2)	8171 (43.4)	3455 (42.8)
Primary site (%)				0.783
Right colon	13053 (48.5)	9139 (48.5)	3914 (48.5)
Left colon	13342 (49.6)	9330 (49.5)	4012 (49.7)
Large intestine, NOS	527 (2.0)	376 (2.0)	151 (1.9)
Histology (%)				0.995
Adenomas/adenocarcinomas	23406 (86.9)	16384 (86.9)	7022 (86.9)
Cystic/mucinous/serous neoplasms	3324 (12.3)	2326 (12.3)	998 (12.4)
Others	192 (0.7)	135 (0.7)	57 (0.7)
Grade (%)				0.055
Well	2775 (10.3)	1992 (10.6)	783 (9.7)
Moderately	18265 (67.8)	12708 (67.4)	5557 (68.8)
Poorly	5094 (18.9)	3603 (19.1)	1491 (18.5)
Undifferentiated	788 (2.9)	542 (2.9)	246 (3.0)
Stage (%)				0.198
Stage 0	204 (0.8)	136 (0.7)	68 (0.8)
Stage I	3939 (14.6)	2792 (14.8)	1147 (14.2)
Stage II	7360 (27.3)	5103 (27.1)	2257 (27.9)
Stage III	9806 (36.4)	6914 (36.7)	2892 (35.8)
Stage IV	5613 (20.8)	3900 (20.7)	1713 (21.2)
T stage (%)				0.437
T0	210 (0.8)	142 (0.8)	68 (0.8)
T1	2595 (9.6)	1845 (9.8)	750 (9.3)
T2	2801 (10.4)	1985 (10.5)	816 (10.1)
T3	15121 (56.2)	10537 (55.9)	4584 (56.8)
T4	6195 (23.0)	4336 (23.0)	1859 (23.0)
N stage (%)				0.259
N0	12410 (46.1)	8645 (45.9)	3765 (46.6)
N1	7886 (29.3)	5576 (29.6)	2310 (28.6)
N2	6626 (24.6)	4624 (24.5)	2002 (24.8)
M stage (%)				0.351
M0	21309 (79.2)	14945 (79.3)	6364 (78.8)
M1	5613 (20.8)	3900 (20.7)	1713 (21.2)
Size (%)				0.871
< 5 cm	9238 (34.3)	6476 (34.4)	2762 (34.2)
≥ 5 cm	9179 (34.1)	6434 (34.1)	2745 (34.0)
Unknown	8505 (31.6)	5935 (31.5)	2570 (31.8)

LNR: Lymph node ratio; LODDS: Log odds of positive lymph node.