Effects of cytoreductive surgery combined with hyperthermic perfusion chemotherapy on prognosis of patients with advanced gallbladder cancer

Table 4 Multivariate Cox regression analysis results

Factors	β	SE	χ2 value	P value	HR	95% CI
						Lower limit	Upper limit
Distant metastasis	0.802	0.319	6.309	0.012	2.230	1.193	4.171
Lymph node metastasis	0.449	0.509	0.777	0.378	1.566	0.578	4.247
Distant metastasis	0.900	0.312	8.289	0.004a	2.459	1.333	4.536
Vascular invasion	0.440	0.273	2.599	0.107	1.552	0.909	2.65
Treatment plan	1.068	0.282	14.377	< 0.001b	2.908	1.675	5.05

^aP < 0.01.

^bP < 0.001.

CI: Confidence interval; HR: Hazard ratio; SE: Standard error.