Effects of cytoreductive surgery combined with hyperthermic perfusion chemotherapy on prognosis of patients with advanced gallbladder cancer

Table 3 Univariate Cox regression analysis results

Factors	β	SE	χ2 value	P value	HR	95%CI
						Lower limit	Upper limit
Age	0.111	0.253	0.195	0.659	1.118	0.681	1.834
Sex	-0.308	0.255	1.460	0.227	0.735	0.446	1.211
Tumor staging	1.212	0.271	19.953	< 0.001b	3.360	1.974	5.719
Differentiation degree	0.255	0.251	1.026	0.311	1.290	0.788	2.111
Comorbid stones	0.126	0.360	0.122	0.727	1.134	0.560	2.296
Tumor size	-0.218	0.254	0.739	0.390	0.804	0.489	1.322
Lymph node metastasis	1.380	0.469	8.650	0.003a	3.976	1.585	9.977
Nerve invasion	0.345	0.257	1.794	0.180	1.411	0.853	2.336
Distant metastasis	1.143	0.308	13.73	< 0.001b	3.135	1.713	5.739
Vascular invasion	0.797	0.260	9.360	0.002a	2.218	1.332	3.696
Treatment plan	0.740	0.262	7.960	0.005a	2.095	1.253	3.503

^aP < 0.01.

^bP < 0.001.

CI: Confidence interval; HR: Hazard ratio; SE: Standard error.