Analysis of textbook outcomes for ampullary carcinoma patients following pancreaticoduodenectomy

Table 4 Univariable and multivariable logistic regression analyses of factors associated with textbook outcome

Characteristic	Univariable analysis		Multivariable analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Year of surgery
1998-2010	Reference		Reference
2011-2020	4.470 (2.361-8.462)	< 0.001	4.549 (2.064-10.028)	< 0.001
Sex
Male	Reference
Female	0.872 (0.495-1.535)	0.634
Age (yr)
≤ 60	Reference
> 60	0.864 (0.487-1.534)	0.618
Operation time (h)
≤ 6	Reference
> 6	1.163 (0.638-2.118)	0.622
Transfusion
No	Reference
Yes	0.758 (0.435-1.321)	0.328
Tumor size (cm)
≤ 2.0	Reference		Reference
> 2.0	1.502 (0.856-2.633)	0.156	1.728 (0.924-3.231)	0.087
Differentiation
Poor	Reference		Reference
Moderate	0.867 (0.471-1.595)	0.646	1.194 (0.597-2.390)	0.616
Well	0.559 (0.248-1.262)	0.162	1.007 (0.360-2.812)	0.990
CA199
0-40	Reference
> 40	1.072 (0.590-1.950)	0.819
Unknown	0.919 (0.331-2.551)	0.872
N stage
N0	Reference		Reference
N1	2.215 (1.192-4.117)	0.012	2.251 (1.023-4.954)	0.044
N2	1.436 (0.434-4.754)	0.554	1.236 (0.314-4.864)	0.762
T stage
T1	Reference		Reference
T2	1.423 (0.599-3.380)	0.424	1.205 (0.455-3.191)	0.707
T3	1.072 (0.464-2.481)	0.870	0.449 (0.150-1.341)	0.151
Lymphovascular invasion
No	Reference		Reference
Yes	2.697 (1.477-4.927)	0.001	1.483 (0.688-3.199)	0.315
Adjuvant treatment
No	Reference		Reference
Yes	0.769 (0.331-1.785)	0.541	1.144 (0.450-2.912)	0.777
Unknown	0.548 (0.267-1.126)	0.102	1.459 (0.629-3.387)	0.379

95%CI: 95% Confidence interval; OR: Odds ratio.