Gene polymorphisms associated with sudden decreases in heart rate during extensive peritoneal lavage with distilled water after gastrectomy

Table 16 Analysis of interaction between rs820196 genotype and smoking and hypertension in patients with heart rate variability ≥ 15% and < 15%

Environment	rs820196 genotype	HRV ≥ 15% (n = 72)	HRV < 15% (n = 120)	OR (95%CI)	P value
Smoking
No	TT	22 (28.95)	54 (71.05)	1.00 (Reference)	-
Yes	TT	5 (45.45)	6 (54.55)	2.12 (0.57, 7.95)	0.26
No	TC	33 (50.00)	33 (50.00)	2.53 (1.26, 5.08)	0.01a
Yes	TC	7 (36.84)	12 (63.16)	1.43 (0.48, 4.22)	0.52
No	CC	3 (17.65)	14 (82.35)	0.48 (0.12, 1.89)	0.30
Yes	CC	2 (66.67)	1 (33.33)	4.68 (0.39, 56.33)	0.22
Hypertension
No	TT	18 (32.73)	37 (67.27)	1.00 (Reference)	-
Yes	TT	9 (28.13)	23 (71.88)	0.77 (0.28, 2.11)	0.62
No	TC	25 (46.30)	29 (53.70)	1.75 (0.80, 3.82)	0.16
Yes	TC	15 (48.39)	16 (51.61)	1.90 (0.75, 4.78)	0.18
No	CC	3 (23.08)	10 (76.92)	0.58 (0.14, 2.42)	0.45
Yes	CC	2 (28.57)	5 (71.43)	0.72 (0.12, 4.26)	0.72

^aP < 0.05 vs nonsmokers with the rs820196 TT.

Logistic regression analyses adjusting for age, gender, and thyroid function. HRV: Heart rate variability; OR: Odds ratio; CI: Confidence interval.