Gene polymorphisms associated with sudden decreases in heart rate during extensive peritoneal lavage with distilled water after gastrectomy

Table 14 Association analysis of interactions between different genotypes of single nucleotide polymorphism loci and risk of heart rate variability ≥ 15%

SNPs genotypes			HRV ≥ 15% (n = 72)	HRV < 15% (n = 120)	OR (95%CI)	P value
rs820196 rs1713449
TT	CC		12 (27.27)	32 (72.73)	1.00 (Reference)	-
TT	CT		10 (27.78)	26 (72.22)	1.03 (0.38, 2.79)	0.95
TT	TT		5 (71.43)	2 (28.57)	6.87(1.15, 41.09)	0.04a
TC	CC		15 (42.86)	20 (57.14)	2.07 (0.79, 5.45)	0.14
TC	CT		22 (55.00)	18 (45.00)	3.26 (1.30, 8.20)	0.01b
TC	TT		3 (30.00)	7 (70.00)	1.06 (0.22, 5.06)	0.94
CC	CC		2 (20.00)	8 (80.00)	0.56 (0.098, 3.21)	0.52
CC	CT		2 (25.00)	6 (75.00)	0.87 (0.15, 5.11)	0.88
CC	TT		1 (50.00)	1 (50.00)	2.90 (0.17, 50.84)	0.47
rs938886 rs1713449 rs820196
GG	CC	TT	12 (27.27)	32 (72.73)	1.00 (Reference)
GG	CC	TC	15 (42.86)	20 (57.14)	1.87 (0.74, 4.77)	0.19
GG	CC	CC	2 (20.00)	8 (80.00)	0.51 (0.09, 2.87)	0.45
GC	CT	TT	10 (27.78)	26 (72.22)	0.93 (0.36, 2.44)	0.89
GC	CT	TC	22 (55.00)	18 (45.00)	2.96 (1.21, 7.22)	0.02c
GC	CT	CC	2 (25.00)	6 (75.00)	0.79 (0.14, 4.57)	0.79
CC	TT	TT	4 (80.00)	1 (20.00)	9.71 (0.97, 96.94)	0.05
CC	TT	TC	3 (30.00)	7 (70.00)	0.98 (0.21, 4.63)	0.98
Others			2 (50.0)	2 (50.0)	-	-

^aP < 0.05 vs TT-CC.

^bP < 0.05 vs TT-CC.

^cP < 0.05 vs GG-CC-TT. Logistic regression analyses adjusting for age, gender, smoking, hypertension, and thyroid function.

SNPs: Single nucleotide polymorphisms; HRV: Heart rate variability; OR: Odds ratio; CI: Confidence interval.