Gene polymorphisms associated with sudden decreases in heart rate during extensive peritoneal lavage with distilled water after gastrectomy

Table 10 Association analysis of the interaction between different genotypes of single nucleotide polymorphism loci and a risk of heart rate variability cutoff value ≥ 30%

SNP genotypes			HRV ≥ 30% (n = 22)	HRV < 30% (n = 170)	OR (95%CI)	P value
rs938886 rs820196
GG	TT		3 (6.67)	42 (93.33)	1.00 (Reference)	-
GG	TC		5 (14.29)	30 (85.71)	2.91 (0.63, 13.55)	0.17
GG	CC		1 (10.00)	9 (90.00)	2.19 (0.19, 25.37)	0.53
GC	TT		3 (8.11)	34 (91.89)	1.65 (0.31, 8.74)	0.56
GC	TC		9 (22.50)	31 (77.50)	6.16 (1.53, 24.83)	0.01a
CC	TT		1 (20.00)	4 (80.00)	5.84 (0.46, 74.57)	0.17
Others			0 (0.00)	20 (100.00)	-	-
rs938886 rs820196 rs1713449
GG	TT	CC	3 (6.82)	41 (93.18)	1.00 (Reference)	-
GG	TC	CC	5 (14.29)	30 (85.71)	2.97 (0.64, 13.79)	0.17
GG	CC	CC	1 (10.00)	9 (90.00)	2.23 (0.19, 25.87)	0.52
GC	TT	CT	3 (8.33)	33 (91.67)	1.73 (0.33, 9.18)	0.52
GC	TC	CT	9 (22.50)	31 (77.50)	6.27 (1.56, 25.28)	0.01b
CC	TT	TT	1 (20.00)	4 (80.00)	5.94 (0.47, 75.98)	0.17
Others			0 (0.00)	22 (100.00)	-	-

^aP < 0.05 vs GG-TT.

^bP < 0.05 vs GG-TT-CC.

Logistic regression analyses adjusting for age, gender, smoking, hypertension, and thyroid function. SNP: Single nucleotide polymorphism; HRV: Heart rate variability; OR: Odds ratio; CI: Confidence interval.