Change of tumor-infiltrating lymphocyte of associating liver partition and portal vein ligation for staged hepatectomy for hepatocellular carcinoma

Figure 8 Changes in peripheral blood lymphocyte subpopulations after stage-I and II associating liver partition and portal vein ligation for staged hepatectomy and right hemi-hepatectomy. Interleukin-6 levels in stage-I associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and stage-II ALPPS increased significantly and reached a peak value on the first day after surgery. Natural killer cells in stage-I and stage-II ALPPS temporarily increased on the first day after surgery and gradually decreased on the second day after surgery to figures lower than the preoperative level. A: T lymphocyte count (/μL); B: CD4⁺ T lymphocyte count (/μL); C: CD8⁺ T lymphocyte count (/μL); D: T lymphocyte percentage (%); E: B lymphocyte percentage (%); F: Treg lymphocyte percentage (%); G: Natural killer cells percentage (%); H: Interleukin-6 (pg/mL). NK: Natural killer; IL: Interleukin; POD: Postoperative day; ALPPS: Associating liver partition and portal vein ligation for staged hepatectomy.