Study of preoperative diagnostic modalities in Chinese patients with superficial esophageal squamous cell carcinoma

Table 4 Diagnostic accuracy of magnifying endoscopy or endoscopic ultrasound according to clinicopathological features

	ME-NBI/BLI		EUS
Features	Accurately assessed lesions (%)	P value	Accurately assessed lesions (%)	P value
Location of esophagus
Cervical	2/2 (100)	0.69	1/2 (50.0)	0.17
Upper thoracic	11/13 (84.6)		9/13 (69.2)
Middle thoracic	60/82 (73.2)		60/82 (73.2)
Lower thoracic	38/55 (69.1)		31/55 (56.4)
Macroscopic type
Elevated	43/60 (71.1)	0.60	40/60 (66.7)	1.00
Flat	67/90 (74.4)		60/90 (66.7)
Depressed	1/2 (50.0)		1/2 (50.0)
Circumferential occupation
< 1/4	26/38 (68.4)	0.38	31/38 (81.6)	0.06
1/4-1/2	35/51 (68.6)		34/51 (66.7)
1/2-3/4	31/37 (83.3)		23/37 (62.2)
≥ 3/4	19/26 (73.1)		13/26 (50.0)
Tumor size
≤ 3 cm	87/121 (71.4)	0.54	85/121 (70.2%)	0.05
> 3 cm	24/31 (77.4)		16/31 (51.6)
Differentiation degree
HGIN or carcinoma in situ	51/60 (85.0)	0.03	43/60 (71.7)	0.54
Good	5/7 (71.4)		4/7 (57.1)
Moderate	48/72 (66.7)		47/72 (65.3)
Poor	7/13 (53.8)		7/13 (53.8)
Endoscopist grade
Junior	33/41 (80.5)	0.21	23/41 (56.1)	0.10
Senior	78/111 (70.3)		78/111 (70.3)
EUS probe
Conventional EUS			36/73 (49.3)	< 0.01
Miniature probe			65/79 (82.3)

ME: Magnifying endoscopy; NBI: Narrow-band imaging; BLI: Blue laser imaging; EUS: Endoscopy ultrasonography; HGIN: High-grade intraepithelial neoplasia; EP: Epithelium; LPM: Lamina propria mucosa; MM: Muscularis mucosa; SM: Submucosa.