Effect of cardiac output - guided hemodynamic management on acute lung injury in pediatric living donor liver transplantation

Table 4 Changes in serum interleukin-6, tumor necrosis factor-α, troponin I, and N-terminal pro-brain natriuretic peptide levels at every time point

		IL-6 (pg/mL)	TNF-α (pg/mL)	cTnI (ug/L)	NT-proBNP (ng/L)
Control group (n = 65)	T0	78.9 ± 23.2	87.5 ± 25.6	0.032 ± 0.015	556.6 ± 251.2
	T1	170.4 ± 42.3b	175.3 ± 43.1b	0.383 ± 0.166b	1012.4 ± 568.8b
	T2	126.2 ± 33.6b	129.5 ± 35.2b	0.182 ± 0.067b	866.0 ± 283.6b
	T3	80.7 ± 23.2	92.8 ± 26.8	0.030 ± 0.011	667.4 ± 247.7
CO-G group (n = 65)	T0	80.6 ± 22.5	83.2 ± 23.8	0.029 ± 0.012	562.2 ± 195.8
	T1	145.5 ± 34.5a,b	156.7 ± 36.1a,b	0.255 ± 0.128a,b	876.7 ± 268.2a,b
	T2	108.6 ± 24.9a,b	115.5 ± 25.6a,b	0.116 ± 0.070a,b	594.0 ± 163.3a,b
	T3	78.6 ± 21.9	86.2 ± 22.6	0.028 ± 0.011	462.6 ± 154.5a,b

^aP < 0.05, compared with control group.

^bP < 0.05, compared with T₀.

Data are expressed as number (%) or mean ± SD. T₀ before induction of general anesthesia, T₁ at the end of surgery, T₂ 1 d after surgery, T₃ 3 d after surgery. CO-G: Cardiac output-guided; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; cTnI: Cardiac troponin I; NT-pro-BNP: N-terminal pro-brain natriuretic peptide.