Effect of cardiac output - guided hemodynamic management on acute lung injury in pediatric living donor liver transplantation

Table 3 Hemodynamic parameters and hemodynamic management

	Control group (n = 65)	CO-G group (n = 65)	P value
Preoperative hemodynamic parameters
HR, bpm/min	110 ± 12	108 ± 11	0.325
MAP, mmHg	60.3 ± 8.0	61.6 ± 9.5	0.382
CVP, cmH2O	6.08 ± 1.37	5.79 ± 1.44	0.241
Intraoperative hemodynamic parameters
HRH, bpm/min	123 ± 15	125 ± 18	0.317
HRL, bpm/min	82 ± 8	86 ± 8	0.003
MAPH, mmHg	72.3 ± 8.8	71.7 ± 10.4	0.531
MAPL, mmHg	34.9 ± 5.5	43.3 ± 7.4	< 0.001
CVPH, cmH2O	11.64 ± 2.1	9.46 ± 1.66	< 0.001
CVPL, cmH2O	4.17 ± 1.49	3.55 ± 1.34	0.013
Intraoperative hemodynamic events
PRS, n (%)	35 (53.8)	22 (33.8)	0.022
Malignant ventricular arrhythmia, n (%)	3 (5)	2 (3.1)	1.000
Cardiac arrest, n (%)	1 (1.5)	0	1.000
Intraoperative hemodynamic management
Intraoperative blood transfusions, U	2.5 (2, 3)	2.0 (1.5, 2.5)	0.821
Intraoperative frozen plasma transfusions, mL	0 (0, 200)	0 (0, 110)	0.751
Intraoperative fluid transfusions, mL	1222.7 ± 381.9	865.5 ± 153.1	< 0.001
Intraoperative bleeding volume, mL	300 (200, 500)	300 (200, 400)	0.543
Intraoperative urinary volume, mL	300 (277.5, 400)	400 (200, 510)	0.416
Positive fluid balance, mL	1021.4 ± 467.9	598.8 ± 320.7	< 0.001
VIS before portal vein opening	2 (2, 5)	3 (2, 6.25)	0.565
During portal vein opening
Bolus injection of epinephrine, n (%)	30 (46.2)	18 (27.7)	0.029
Bolus dosage of epinephrine, μg	3 (2, 5)	2.5 (1.75, 4.25)	0.030
VIS after portal vein opening	3 (2, 7)	2 (2, 3)	0.049

Data are expressed as number (%), mean ± SD, or median (interquartile range), as appropriate. CO-G: Cardiac output-guided; HR: Heart rate; MAP: Mean arterial blood pressure; CVP: Central venous pressure; HR_H: Intraoperative maximum heart rate; HR_L: Intraoperative minimum heart rate; MAP_H: Intraoperative maximum mean arterial blood pressure; MAP_L: Intraoperative minimum mean arterial blood pressure; CVP_H: Intraoperative maximum central venous pressure; CVP_L: Intraoperative minimum central venous pressure; PRS: Postreperfusion syndrome; VIS: Vasoactive inotropic score.