Model established based on blood markers predicts overall survival in patients after radical resection of types II and III adenocarcinoma of the esophagogastric junction

Table 2 Univariate analysis of adenocarcinoma of the esophagogastric junction (types II and III) patients

Characteristic	Coefficient	HR (95%CI)	P value
Gender (men/women as reference)	0.078	1.081 (0.765, 1.528)	0.660
Age	0.019	1.019 (1.002, 1.037)	0.031
NLR	0.176	1.193 (1.112, 1.280)	< 0.001
Tumor size	0.178	1.195 (1.134, 1.260)	< 0.001
TNM stage	1.042	2.836 (2.046, 3.930)	< 0.001
Histologic type	0.390	1.477 (1.086, 2.009)	0.013
CA199	0.000	1.000 (0.998, 1.002)	0.948
PNI	-0.034	0.966 (0.940, 0.993)	0.013
PLR	0.003	1.003 (1.001, 1.005)	0.009
Fibrinogen	0.010	1.030 (0.970, 1.095)	0.332
Albumin	-0.289	0.557 (0.479, 1.008)	0.056
Prealbumin	-0.102	0.362 (0.271, 0.484)	< 0.001
Surgery time	0.017	1.017 (0.755, 1.369)	0.912
BMI	-0.580	0.560 (0.431, 0.727)	< 0.001
Cancerous node	0.219	1.245 (1.150, 1.347)	< 0.001
Hemoglobin	-0.006	0.994 (0.988, 1.000)	0.033
Tumor location	0.719	1.127 (0.855, 1.487)	0.397
Smoking	0.006	0.994 (0.970, 1.019)	0.624
Comorbidities	0.017	0.983 (0.953, 1.013)	0.264

NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; BMI: Body mass index; PNI: Prognostic nutritional index; CEA: Carcinoembryonic antigen.