Impact of comorbid renal dysfunction in patients with hepatocellular carcinoma on long-term outcomes after curative resection

Table 6 Postoperative complications in the patients with severe and mild chronic kidney disease and without renal dysfunction

	CKD stage			P value
	Severe (EGFR < 30), n = 19	Mild (30 ≤ EGFR < 60), n = 109	Non-RD (EGFR ≥ 60), n = 672
All complications	5 (26.3)	28 (25.7)	169 (25.1)	0.99
Major complication (Grade ≥ 2)	3 (15.8)	17 (15.6)	112 (16.7)	0.98
Bile leakage	2 (10.5)	10 (9.2)	44 (6.5)	0.40
Ascites	2 (10.5)	4 (3.7)	27 (4.0)	0.45
Pleural effusion	0 (0.0)	4 (3.7)	37 (5.5)	0.68
Pneumonia	1 (5.3)	5 (4.6)	12 (1.8)	0.84
Bleeding	2 (10.5)	5 (4.6)	12 (1.8)	< 0.05
Liver failure	0 (0.0)	1 (0.9)	9 (1.3)	0.55
Surgical site infection	0 (0.0)	5 (4.6)	12 (1.8)	0.07
Duration of postoperative hospital stay (d)	16.0 ± 15.3	16.0 ± 14.4	16.0 ± 9.3	0.92
Died during hospitalization	0 (0.0)	11 (0.9)	12 (0.1)	0.96

¹One patient in the renal dysfunction group died due to postoperative gastrointestinal perforation and an intraabdominal abscess.

²One patient in the non-renal dysfunction group died due to postoperative liver failure.

P values were determined by the χ² test or the Mann-Whitney U test. RD: Renal dysfunction; CKD: Chronic kidney disease; EGFR: Estimated glomerular filtration rate.