Comparison between laparoscopic uncut Roux-en-Y and Billroth II with Braun anastomosis after distal gastrectomy: A meta-analysis

Table 3 Subgroup analysis of all the outcomes according to study type

Subgroup	Type	No. of studies	No. of patients		Meta-analysis results		Assessment of heterogeneity
			URY	BB	OR/MD (95%CI)	P value	I²	P value
Operative time	RCTs	3	136	136	0.93 [(-5.87)-7.73]	0.79	0	0.95
	Non-RCTs	4	182	175	1.71 [(-7.09)-10.51]	0.70	0	0.82
Reconstruction time	RCTs	2	92	92	3.32 [(-3.85)-10.49]	0.36	0.92	0.0005
	Non-RCTs	4	137	156	-0.41 [(-3.85)-3.03]	0.81	0.74	0.0009
Intraoperative blood loss	RCTs	3	136	136	3.87 [(-7.02)-14.75]	0.49	0.45	0.16
	Non-RCTs	4	218	214	0.58 [(-2.60)-3.77]	0.72	0	0.91
Total number of harvested lymph nodes	RCTs	2	92	92	0.15 [(-1.86)-2.16]	0.88	0	0.98
	Non-RCTs	3	163	147	1.90 [(-0.14)-3.94]	0.07	0	0.39
Time to first passage of flatus or defecation	RCTs	2	106	106	-0.26 [(-0.87)-0.34]	0.40	0.77	0.04
	Non-RCTs	5	218	214	-0.29 [(-0.59)-0.01]	0.05	0.56	0.06
Time to first solid diet	RCTs	1	44	44	-0.05 [(-1.14)-1.04]	0.93	Not applicable
	Non-RCTs	4	173	164	-0.29 [(-0.53)-(-0.05)]	0.02	0	0.67
Postoperative hospitalization time	RCTs	2	106	106	-0.01 [(-0.16)-0.14)]	0.87	0	0.84
	Non-RCTs	5	218	214	-0.26 [(-0.78)-0.26]	0.32	0	0.63
Reflux gastritis	RCTs	2	92	92	0.03 (0.01-0.11)	< 0.00001	0	0.70
	Non-RCTs	3	193	209	0.15 (0.03-0.66)	0.01	0	0.77
Anastomotic leakage	RCTs	2	106	106	0.73 (0.15-3.48)	0.69	Not applicable
	Non-RCTs	3	107	123	1.16 (0.23-5.87)	0.85	0	0.85

URY: Uncut Roux-en-Y; BB: BII combined Braun; RCTs: Randomised controlled trials; OR: Odds ratio; MD: Mean difference; CI: Confidence interval.