Comparison between laparoscopic uncut Roux-en-Y and Billroth II with Braun anastomosis after distal gastrectomy: A meta-analysis

Table 1 Characteristics of the included studies

Ref.	Study type	Country	Period	Number (URY/BB)	Gender (M/F)	Age (URY/BB)	BMI	ASA (I/II/III)	Tumor stage (I/II/III/IV)	Differentiation (H/M/L)	Matched factors1	NOS score
Chen[30], 2018	RCT	China	2016.5-2017.9	URY 30, BB 30	17/13, 16/14	55.00 ± 5.40, 53.50 ± 7.56	22.89 ± 4.23, 21.38 ± 2.02	NR	3/10/17/0, 4/12/14/0	5/15/10, 4/14/12	1, 2, 3, 4, 7, 8, 12	NA
Gao and Xiang[29], 2018	Retro	China	2014.1-2017.1	URY 26, BB 34	17/9, 21/13	60.61 ± 11.14, 59.72 ± 10.79	21.58 ± 1.86, 21.35 ± 1.93	NR	0/5/14/7, 0/7/18/9	8/7/11, 10/11/13	1, 2, 3, 5, 6, 9, 10, 11, 12, 13	8
Li et al[32], 2017	Retro	China	2010.1-2016.1	URY 30, BB 33	21/9, 21/12	52.81 ± 5.39, 52.09 ± 6.47	21.66 ± 2.54, 21.81 ± 2.62	NR	NG	8/11/11, 9/12/12	1, 2, 3, 5, 6, 9, 12	7
Ren et al[31], 2020	RCT	China	2015.6-2016.12	URY 44, BB 44	30/14, 28/16	59.61 ± 11.14, 59.72 ± 10.79	21.51 ± 1.86, 21.38 ± 1.93	NR	0/8/25/11, 0/9/23/12	14/13/17, 13/14/17	1, 3, 5, 6, 9, 10, 11, 13	NA
Wang et al[36], 2018	Retro	China	2015.3-2017.6	URY 81, BB 58	52/29, 46/12	56 (30-79), 56.5 (24-77)	NR	NR	41/20/17/0, 28/13/16/0	NR	1, 3, 4, 5, 6, 9	8
Wang et al[34], 2021	RCT	China	2017.1-2018.5	URY 62, BB 62	44/18, 44/18	54.84 ± 8.31; 54.69 ± 10.07	22.43 ± 3.07, 22.46 ± 3.17	27/28/7, 16/41/5	NG	NR	1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12	NA
Wu et al[33], 2021	Retro	China	2016.1-2019.4	URY 45, BB 50	27/18, 31/19	59.1 ± 6.2, 59.1 ± 6.3	23.3 ± 3.0, 23.2 ± 2.9	NR	45/0/0/0, 50/0/0/0	7/15/23, 8/19/23	1, 2, 3, 4, 5, 9, 10, 11, 12, 13	6
Zhou et al[35], 2018	Retro	China	2010.6-2015.4	URY 36, BB 39	22/14, 24/15	61 ± 5, 61 ± 8	23 ± 3, 22 ± 4	21/15/0, 23/16/0	36/0/0/0, 39/0/0/0	11/16/9, 10/19/10	2, 3, 4, 5, 6, 9, 10, 13	8

¹Outcomes: (1) Operative time; (2) Reconstruction times; (3) Intraoperative bleeding; (4) Total number of harvested lymph nodes; (5) Time to first passage of flatus or defecation; (6) Time to first solid diet; (7) Mean gastric pH at day 1; (8) Mean gastric pH at day 3; (9) Post-operative hospitalization time; (10) Anastomotic leakage; (11) Ileus; (12) Reflux gastritis; and (13) Gastroparesis.

ASA: American Society of Anesthesiologists score; BMI: Body mass index; NOS: Newcastle-Ottawa Scale; NR: Not reported; Retro: Retrospective observational study; NA: Not applicated; RCT: Randomised controlled trial; URY: Uncut Roux-en-Y; BB: BII combined Braun; NG: Not given.