Transjugular intrahepatic portosystemic shunt with radioactive seed strand for main portal vein tumor thrombosis with cirrhotic portal hypertension

doi:10.4240/wjgs.v14.i6.567

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Jun 27, 2022 (publication date) through Nov 4, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. Jun 27, 2022; 14(6): 567-579
Published online Jun 27, 2022. doi: 10.4240/wjgs.v14.i6.567

Table 1 Baseline characteristics of patients

Characteristics	n (%)/mean ± SD/M (P₂₅-P₇₅)
Gender (male/female)	70/13 (84.3/15.7)
Age (yr)	56.46 ± 8.97
BMI	22.83 ± 2.99
Etiology of cirrhosis (HBV/HCV/alcoholic/other)	66/8/4/5 (79.5/9.6/4.8/6.0)
Cirrhosis-related decompensated events (EGVB/Refractory ascites or hydrothorax/Both)	62/14/7 (74.7/16.9/8.4)
EGV degree (mild/moderate/severe)	7/36/40 (8.4/43.4/48.2)
Ascites degree (no/mild/moderate-severe)	8/24/51 (9.6/28.9/61.4)
Preoperative HVPG (mmHg)	19.96 ± 9.01
Child–Pugh grade (A/B/C)	23/52/8 (27.7/62.7/9.6)
Intrahepatic HCC morphology (unifocal/multifocal)	47/36 (56.6/43.4)
Sum of longest viable tumor diameters (cm)	6.62 ± 2.77
≤ 5/5-8/> 8	23/44/16 (27.7/53.0/19.3)
BCLC stage (C/D)	75/8 (90.4/9.6)
cTNM stage (IIIB/IVA/IVB)	55/19/9 (66.3/22.9/10.8)
PLT (10⁹/L)	108.24 ± 86.09
PT (s)	14.89 ± 3.89
ALT (U/L)	31.40 ± 29.29
AST (U/L)	49.63 ± 45.00
TBil (μmol/L)	31.74 ± 17.68
Albumin (g/L)	35.08 ± 4.85
AFP (ng/mL)¹	769.49 (16.69-2345.11)
Log₁₀(AFP)	2.40 ± 1.26
Combined TACE/RFA/targeted therapy	83/52/41 (100/62.7/49.4)

¹Skewness distribution. The upper limit of AFP detection is 20000 ng/mL. BMI: Body mass index; HBV: Hepatitis B virus; HCV: Hepatitis C virus; EGVB: Esophagogastric variceal bleeding; EGV: Esophagogastric varices; HVPG: Hepatic venous pressure gradient; HCC: Hepatocellular carcinoma; PLT: Platelet; PT: Prothrombin time; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBil: Total bilirubin; AFP: Alpha-fetoprotein; TACE: Transarterial chemoembolization; RFA: Radiofrequency ablation.

Citation: Yan XH, Yue ZD, Zhao HW, Wang L, Fan ZH, Wu YF, Meng MM, Zhang K, Jiang L, Ding HG, Zhang YN, Yang YP, Liu FQ. Transjugular intrahepatic portosystemic shunt with radioactive seed strand for main portal vein tumor thrombosis with cirrhotic portal hypertension. World J Gastrointest Surg 2022; 14(6): 567-579
URL: https://www.wjgnet.com/1948-9366/full/v14/i6/567.htm
DOI: https://dx.doi.org/10.4240/wjgs.v14.i6.567