Short and long-term outcomes between laparoscopic and open total gastrectomy for advanced gastric cancer after neoadjuvant chemotherapy

Table 6 Clinical characteristics and perioperative index in ypTNM III-IV patients after neoadjuvant chemotherapy (mean ± SD)

Variable	LTG group (n = 30)	OTG group (n = 35)	P value
Gender			0.931
Male	22	26
Female	8	9
Age (yr)	55.97 ± 10.10	55.94 ± 12.90	0.993
BMI (kg/m2)	23.03 ± 2.60	23.63 ± 3.73	0.468
CCI score			0.514
0-2	21	27
> 2	9	8
Tumor diameter, cm	5.5 (3.5-8.0)	5.0 (4.0-8.0)	0.916
Surgical time, min	250.17 ± 42.99	239.34 ± 45.69	0.332
Blood loss, mL (median, IQR)	200 (100-350)	300 (200-400)	0.159
Blood loss (mL), n (%)			0.404
0-200	12	8
200-400	11	20
> 400	7	7
Retrieved lymph nodes, n	32.73 ± 11.24	32.89 ± 15.58	0.965
Time to first flatus, d	4.40 ± 1.30	5.37 ± 1.09	0.002
Postoperative stay, d	10.03 ± 4.30	12.17 ± 3.73	0.036
Surgery costs, $	4793.57 (4032.20-6242.77)	3871.55 (3686.28-4416.86)	0.000
Hospitalization costs, $	13190.05 (12036.98-14591.47)	15263.28 (13162.85-17143.01)	0.000
Total complication rate (%), C-D classification	9 (30.0)	12 (34.3)	0.647
II	8	11
IIIa	1	1
Severe complication rate (%)	1 (3.3)	1 (2.9)	1.000

LTG: Laparoscopic total gastrectomy; OTG: Open total gastrectomy; NACT: Neoadjuvant chemotherapy; CCI: Comprehensive complication index; BMI: Body mass index; C-D classification: Clavien-Dindo classification.