Short and long-term outcomes between laparoscopic and open total gastrectomy for advanced gastric cancer after neoadjuvant chemotherapy

Table 5 Clinical characteristics and perioperative indexes in ypTNM 0-II patients after neoadjuvant chemotherapy (mean ± SD)

Variable	LTG group (n = 31)	OTG group (n = 40)	P value
Gender			0.841
Male	25	33
Female	6	7
Age (yr)	59.10 ± 10.51	57.63 ± 11.16	0.574
BMI (kg/m2)	22.58 ± 2.77	23.72 ± 2.93	0.102
CCI score			0.594
0-2	22	26
> 2	9	14
Tumor diameter, cm (median, IQR)	3.00 (2.20-4.50)	2.30 (1.42-4.00)	0.158
Surgical time, min	260.97 ± 37.20	237.93 ± 35.51	0.010
Blood loss, mL (median, IQR)	150 (100-200)	200 (200-300)	0.002
Blood loss (mL), n (%)			0.000
0-200	19	5
200-400	9	31
> 400	3	4
Retrieved lymph nodes, n	34.00 ± 15.11	36.38 ± 17.64	0.552
Time to first flatus, d	4.32 ± 1.28	5.45 ± 1.24	0.000
Postoperative stay, d	8.94 ± 3.63	11.65 ± 3.03	0.001
Surgery costs, $	5641.18 ± 1351.17	4163.48 ± 627.86	0.000
Hospitalization costs, $	13389.70 ± 2254.38	15024.88 ± 23358.95	0.004
Total complication rate (%), C-D classification	5 (16.1)	9 (22.5)	0.503
II	4	8
IIIa	0	1
V	1	0
Severe complication rate (%)	1(3.2)	1 (2.5)	1.000

LTG: Laparoscopic total gastrectomy; OTG: Open total gastrectomy; NACT: Neoadjuvant chemotherapy; CCI: Comprehensive complication index; BMI: Body mass index; C-D classification: Clavien-Dindo classification