Short and long-term outcomes between laparoscopic and open total gastrectomy for advanced gastric cancer after neoadjuvant chemotherapy

Table 3 Neoadjuvant chemotherapy characteristics

Variable	LTG group (n = 61)	OTG group (n = 75)	P value
Number of cycles of NACT			0.467
1-2	13	12
3-4	45	59
> 4	3	4
NACT regimen			0.143
SOX	48	65
XELOX	8	9
Other	5	1
Clinical response			0.659
CR	1	7
PR	28	29
SD	28	34
PD	4	5
Adverse effects after NACT			0.535
Grade 0	13	17
Grade I	16	21
Grade II	17	23
Grade III	11	12
Grade IV	4	2
Chemotherapy–surgical procedure interval (wk)	5.07 ± 1.67	4.55 ± 1.33	0.047
Adjuvant therapy			0.545
Yes	52	61
No	9	14

LTG: Laparoscopic total gastrectomy; OTG: Open total gastrectomy; NACT: Neoadjuvant chemotherapy; CR: Complete response; PR: Partial response; PD: Progressive disease.