Para-aortic lymph node involvement should not be a contraindication to resection of pancreatic ductal adenocarcinoma

Table 3 Risk analysis for disease-free survival

	Univariable		Multivariable
	P value	HR (CI)	P value	HR (CI)
Age	0.129	0.979 (0.952-1.006)	0.023	0.964 (0.933-0.995)
Sex	0.881	0.955 (0.526-1.736)
Preoperative CA19-9	0.773	1.000 (1.000-1.000)
Preoperative stage	0.943	1.016 (0.656-1.573)
Resection type	0.215	1.272 (0.869-1.862)
Venous resection	0.739	0.899 (0.481-1.681)
Arterial resection	0.567	0.048 (0.000-1578.950)
pT	0.002	2.102 (1.308-3.378)	0.004
pT1			0.265	1.726 (0.661-4.509)
pT2			0.015	3.689 (1.287-10.576)
pT3			0.002	49.543 (4.018-610.815)
pN	0.121	1.387 (0.917-2.097)
PALN positivity	0.101	1.748 (0.896-3.410)	0.045	2.287 (1.018-5.136)
Margin status	0.032	1.927 (1.057-3.514)	0.007	2.48 (1.275-4.822)
Perineural invasion	0.103	2.084 (0.862-5.036)	0.041	2.938 (1.045-8.255)
Perivascular invasion	0.152	1.657 (0.830-3.308)
Chemotherapy	0.047	0.509 (0.261-0.992)	0.001	0.242 (0.105-0.559)

All parameters with P < 0.200 on univariable entered into multivariable model. HR: Hazard ratios; CI: Confidence intervals; PALN: Para-aortic lymph nodes.