How to examine anastomotic integrity intraoperatively in totally laparoscopic radical gastrectomy? Methylene blue testing prevents technical defect-related anastomotic leaks

doi:10.4240/wjgs.v14.i4.315

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Apr 27, 2022 (publication date) through Nov 4, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Apr 27, 2022; 14(4): 315-328
Published online Apr 27, 2022. doi: 10.4240/wjgs.v14.i4.315

Table 5 Risk factors for positive intraoperative methylene blue testing and postoperative anastomotic leaks analyzed by multivariate analysis

Variable	B	Standard deviation	Wald	Exp(B)	Odds ratio (95%CI)		P value
Variable	B	Standard deviation	Wald	Exp(B)	Lower limit	Upper limit	P value
IMBT
BMI ≥ 25 kg/m²	2.123	0.810	6.862	8.357	1.707	40.922	0.009
Neoadjuvant chemotherapy	1.326	0.805	2.715	3.767	0.778	18.245	0.099
Operation time ≥ 4 h	4.023	1.319	9.303	55.881	4.212	741.381	0.002
Inexperienced surgeons	2.727	1.052	6.719	15.286	1.944	120.167	0.010
PAL
BMI > 25 kg/m²	1.289	0.858	2.259	3.630	0.676	19.498	0.133
Preoperative complications	2.575	1.081	5.671	13.128	1.577	109.268	0.017
Neoadjuvant chemotherapy	1.967	0.740	7.063	7.150	1.676	30.506	0.008
TLTG	2.206	1.091	4.083	9.075	1.069	77.070	0.043

IMBT: Intraoperative methylene blue testing; PAL: Postoperative anastomotic leak; BMI: Body mass index; TLTG: Totally laparoscopic total gastrectomy.

Citation: Deng C, Liu Y, Zhang ZY, Qi HD, Guo Z, Zhao X, Li XJ. How to examine anastomotic integrity intraoperatively in totally laparoscopic radical gastrectomy? Methylene blue testing prevents technical defect-related anastomotic leaks . World J Gastrointest Surg 2022; 14(4): 315-328
URL: https://www.wjgnet.com/1948-9366/full/v14/i4/315.htm
DOI: https://dx.doi.org/10.4240/wjgs.v14.i4.315