Successful treatment with laparoscopic surgery and sequential multikinase inhibitor therapy for hepatocellular carcinoma: A case report

Figure 3 Pathological findings of metastatic splenic lesions. A: Macroscopic finding shows that splenic lesions surrounded by fibrous capsule, and a border part (blue area) is distinguished from other parts (yellow area) with its color, suggesting viable lesions; B: Microscopic finding of viable tumor lesion shows moderately to poorly differentiated hepatocellular carcinoma. Hematoxylin-eosin stain, high-power field (× 200); C: Microscopic findings of mixed component of viable cells and necrotic tissue demonstrated that coagulative and partially liquefactive necrosis (right-side) is surrounded by fibrous capsule, and viable cells (left-side). Hematoxylin-eosin stain, low-power field (× 50); D: Gamma-Gandy bodies shown in the splenic lesions, suggesting previous history of portal hypertension due to portal vein tumor thrombosis. Hematoxylin-eosin stain, high-power field (× 200).