Peroral endoscopic longer vs shorter esophageal myotomy for achalasia treatment: A systematic review and meta-analysis

Table 2 The detailed study quality evaluation items

Ref.	Follow-up sample	Length of the myotomy, cm	Operative time, min	Myotomy length, cm	Follow-up time, mo	Clinical success	GERD, %	LESP, mmHg	HRM, mmHg	Post-ECK scores	Adverse events
Familiari et al[15], 2016	LM: 23 SM: 26	LM: 13 SM: 8	LM: 59.2 ± 16.7 SM: 47.7 ± 13.2	ES: LM: 8.42 ± 2.13 SM: 3.87 ± 0.61 ST: LM: 2.49 ± 0.70 SM: 2.21 ± 0.41 TO: LM: 10.94 ± 2.11 SM: 6.04 ± 0.69	8	LM: 100% SM: 100%	LM: 42.9% SM: 65%	LM: 17 ± 9.7 SM: 11.4 ± 6.5	LM: 8.6 ± 4.9 SM: 5.9 ± 5.0	LM: 0.5 ± 0.8 SM: 0.5 ± 0.8	No
Gao et al[16], 2017	LM: 53 SM: 47	LM: > 7 SM: ≤7	LM: 63.13 ± 26.5 SM: 50.62 ± 20.02	NA	3,6,12	LM: 96.2% SM: 93.6%	LM: 11.3% SM: 12.8%	LM: 16.51 ± 5.01 SM: 17.41 ± 3.69	NA	LM: 0.98 ± 1.14 SM: 1.06 ± 1.42	MB: LM: 0, SM: 0 MP: LM: 1; SM: 0 HS: LM: 10.19 ± 4.03 SM: 10.21 ± 3.78
Gong et al[17], 2016	LM: 59 SM: 38	LM: > 7 SM: ≤7	LM: 68.5 ± 23.2 SM: 44.2 ± 16.3	ES: LM: 8.5 ± 2.6 SM: 4.0 ± 0.9 ST: LM: 3.2 ± 1.4 SM: 2.1+0.3 TO: LM: 11.7 ± 2.4 SM: 6.1 ± 0.5	NA	LM: 91.5% SM: 92.1%	LM: 18.6% SM: 15.8%	LM: 19.3 ± 8.5 SM: 16.7 ± 4.3	NA	LM: 1.2 ± 1.2 SM: 1.0 ± 0.9	MB: LM: 3; SM: 2 MP: LM: 1; SM: 0 HS: LM: 6.6 ± 1.1 SM: 6.4 ± 1.2
Gu et al[14], 2020	LM: 48 SM: 46	LM: 7-8 SM: 3-4	LM: 45.6 ± 16.2 SM: 31.2 ± 15.3	ES: LM: 10.14 ± 0.54 SM: 5.66 ± 0.14	1,3,6,12	LM: 93.8% SM: 95.7%	LM: 22.9% SM: 15.2%	LM: 12.1 ± 3.9 SM: 11.8 ± 4.4	LM: 9.7 ± 2.6 SM: 10.1 ± 2.4	LM: 0.72 ± 0.42 SM: 0.76 ± 0.51	HS: LM: 6: 5 ± 1.6 SM: 7.0 ± 0.9
Huang et al[13], 2020	LM: 74 SM: 36	LM > 7 SM≤ 7	LM: 62.1 ± 25.2 SM: 46.6 ± 18.5	ES: LM: 8.2 ± 2.7 SM: 4.0 ± 0.7 ST: LM: 3.2 ± 1.2 SM: 3.2 ± 1.2 TO: LM: 11.5 ± 3.1 SM: 6.0 ± 0.6	28.7	LM: 91.9% SM: 94.4%	LM: 14.9% SM: 8.3%	LM: 13.3 ± 5.7 SM: 15.9 ± 3.2	NA	LM: 1.6 ± 1.3 SM: 1.3 ± 1.2	MB: LM: 3; SM: 2 MP: LM: 1; SM: 0 HS: LM: 9.3 ± 2.9 SM: 9.9 ± 2.4
Nabi et al[12], 2020	LM: 37 SM: 34	LM: ≥ 6 SM: ≤ 3	LM: 72.43 ± 27.28 SM: 44.03 ± 13.78	ES: LM: 7.97 ± 2.40 SM: 2.76 ± 0.41 ST: LM: 2.84 ± 0.63 SM: 2.70 ± 0.73	12	LM: 96.97% SM: 93.55%	LM: 56.67%SM: 44.4%	NA	LM: 7.44 ± 4.30 SM: 8.60 ± 1.30	LM: 0.818 ± 0.983 SM: 0.935 ± 0.929	MB: LM: 17; SM: 12 HS: LM: 2.81 ± 0.70 SM: 2.82 ± 0.67

Data are presented as mean ± standard deviation or n (%). Eck: Eckardt score; ES: Esophageal; HS: Hospitalization, mean days; MB: Major bleeding; MP: Mucosal perforation; Post-ECK scores: Postoperative- peroral endoscopic myotomy Eckardt scores; POEM: Peroral endoscopic myotomy; GERD: Gastroesophageal reflux disease; LM: Long myotomy; NA: Not Applied; SM: Short myotomy; ST: Stomach; TO: Total.