Choledocholithiasis characteristics with periampullary diverticulum and endoscopic retrograde cholangiopancreatography procedures: Comparison between two centers from Lanzhou and Kyoto

Table 3 Comparison of clinical characteristics of choledocholithiasis patient with and without periampullary diverticulum in Lanzhou or Kyoto

Clinical Item	Lanzhou (n = 2702)			Kyoto (n = 613)
	Non-PAD, n = 1873	PAD, n = 829	P	Non-PAD, n = 372	PAD, n = 241	P
Age, (median)	56.1 ± 16.9	64.6 ± 13.6	< 0.001	71.0 ± 15.0	75.7 ± 12.1	< 0.001
Gender, n (%)			< 0.001			0.22
Male	842 (45.0)	448 (54.0)		210 (56.4)	124 (51.4)
Female	1031 (55.1)	381 (46.0)		162 (43.6)	117 (48.6)
Proportion of CBD stone, n (%)			0.002			0.69
Single-stone	1131 (61.0)	449 (54.7)		298 (81.0)	188 (79.7)
Multiple-stone	724 (39.0)	372 (45.3)		70 (19.0)	48 (20.3)
Maximum diameter of CBD stone (mean ± SD, mm)	10.3 ± 5.4	12.2 ± 6.5	< 0.001	7.5 ± 5.2	8.2 ± 5.3	0.11
Diameter of CBD (mean ± SD, mm)	13.4 ± 5.1	14.8 ± 5.2	< 0.001	10.9 ± 3.6	11.6 ± 4.2	0.06
Cholecystectomy	14.5 ± 5.5	15.5 ± 5.2	0.008	11.3 ± 2.7	13.1 ± 4.8	0.25
Gallbladder in situ	12.7 ± 4.6	14.4 ± 5.1	< 0.001	10.9 ± 3.6	11.5 ± 4.2	0.07
Concomitant disease, n (%)
Acute cholangitise	260 (13.9)	153 (18.5)	0.002	39 (10.5)	23 (9.5)	0.71
Gallbladder stone	129 (6.9)	39 (4.7)	0.03	43 (11.6)	30 (12.5)	0.74
Obstructive jaundice	311 (16.6)	114 (13.8)	0.06	0 (0.0)	1 (0.4)
Past medical history, n (%)
Operation Billroth I	6 (0.3)	0 (0.0)	0.19	8 (2.2)	3 (1.2)	0.54
Operation Billroth II	5 (0.3)	5 (0.6)	0.19	4 (1.1)	1 (0.4)	0.65
Cholecystectomy	738 (39.4)	318 (38.4)	0.61	16 (4.3)	9 (3.7)	0.73
Billary tract surgery	89 (4.8)	34 (4.10)	0.45	0 (0.0)	0 (0.0)

PAD: Periampullary diverticulum.